How does Adderall work in the brain? Adderall affects the activity of two important chemical messengers dopamine and norepinephrine that help regulate attention, motivation, alertness and impulse control. It is a prescription stimulant used primarily to treat attention-deficit/hyperactivity disorder (ADHD) and, for certain formulations, narcolepsy. Adderall contains a combination of amphetamine and dextroamphetamine. These medicines […]